What is Viagra

Viagra is a brand name of a medication based on Sildenafil Citrate and manufactured by Pfizer. Viagra is used to treat erectile dysfunction.

Sildenafil delivers blood to the pelvic organs including male genitals, Due to this effect, Viagra is beneficial for erectile dysfunction.

Pfizer also manufactures Revatio on the base of Sildenafil Citrate. But this medication is used to treat pulmonary hypertension.

The Viagra story. Production

The story of how Viagra was developed and how it was discovered that Sildenafil is beneficial for sexual vigor is rather unusual.

In the 90s, the company Pfizer was developing a medication to treat heart diseases. They had a special interest in Sildenafil Citrate. They believed that the substance could improve the circulation in the heart decreasing blood pressure.

In 1992 in a British city Sandwich, Sildenafil was clinically tested and the results showed its ineffectiveness. The substance didn’t provide the expected impact and didn’t significantly improve the circulation in the heart.

However, some of the subjects were not willing to give Sildenafil drugs back. The subjects were all men. Later, it was found out that all men experienced better erectile dysfunction after taking Sildenafil.

In Pfizer, they came to conclusion that while Sildenafil does not impact the circulation in the heart, it improves the circulation in the male reproductive organs.

The studies continued but in a different field. The company started developing a medication to treat erectile dysfunction.

The clinical studies of Sildenafil began in 1993. By 1998, its effectiveness and safety was confirmed and the US Food and Drug Administration approved Viagra (Sildenafil).

What you should know before taking Viagra

Viagra and other drugs. Contraindications and side effects

Before you start using Viagra to treat erectile dysfunction, you want to consult your doctor. It is important to tell your doctor what other medications you are taking at the moment. Some drugs may cause unwanted side effects when used with Viagra.

Viagra is incompatible with nitrates including nitroglycerin. This combination of drugs causes a sharp drop in blood pressure. The same effect occurs when you take Viagra and “poppers”.

Do not take Viagra with drugs of similar action such as Cialis, Levitra, and Stendra. Do not take Viagra while also taking Revatio because these drugs have the same active substance.

Taking Viagra and other medications for erectile dysfunction only after consulting your doctor.

Alcohol reduces the effectiveness of Sildenafil. Besides, it can cause a drop in blood pressure.

It is not recommended to take Viagra and grapefruits or grapefruit juice.

Men over 65 years old may experience more pronounced side effects than younger men, so they should take Viagra with caution.

Side effects

While the safety of Viagra is acknowledged, like other medications it may have side effects. Among them are the following:

  • Relatively common side effects include intestinal disorders such as indigestion. Other than this, muscular pain, backache and headache may occur.
  • Sometimes runny and stuffy nose, nasal bleeding, low blood pressure and insomnia occur.
  • In rare cases, patients with predisposition may experience loss of vision. It is caused by decreased blood flow to the optical nerve. Diabetic patients, smokers, men with heart and vision disorders, and high cholesterol have a greater risk to develop this side effect.
  • Another rare side effect is painful erection that may last 4 hours and more.

Viagra side effects that require an immediate call for the doctor

Pronounced side effects after taking Viagra occur in rare cases but certain symptoms and conditions require an immediate medical consultation.

  • Allergic reaction that includes itchy skin, rash, flaky skin, edema, redness, blisters.
  • Difficulty breathing and swallowing, swollen lips, throat, face.
  • Severe headaches.
  • Lightheadedness and faintness.
  • Pain and tightness in the chest, irregular heart rhythm. Vomiting for no apparent cause.
  • Vision changes or loss.
  • Hearing changes or loss, ringing on the ears.
  • Shortness of breath for no apparent cause.
  • Swollen extremities.
  • Fever.
  • Bruises and bleeding for no apparent cause.

Dosage and use

Dosage of Viagra is determined by your doctor depending on your health. You can not increase or decrease the dosage. Viagra should not be taken for a longer period than it has been prescribed.

A recommended starting dose for healthy men is 50 mg. Your doctor may recommend to lower the dose to 25 mg or increase it to 100 mg but never more than this because this is the maximum daily dose.

Take Viagra once a day an hour before an intercourse. Viagra is effective for 30 minutes to 4 hours after you take it.

Viagra absorbs well without regard to food.

Erection does not occur after you take the drug. Sexual stimulation is needed.

Viagra generics

What are generics

Generic is a pharmaceutical product with the active substance that was already used in the original medication.

Development of a drug with a new active substance is a long and expensive process. Pharmaceutical companies invest a lot of money in drug development and tests and studies. Only when the results of the studies are positive – which is not always the case – the drug is brought to the market.

The company receives a patent to manufacture and sell the drug. While the patent is in force, no other company is allowed to produce drugs with this new active substance. Selling their original drugs, the company covers their costs for the development.

Later, when the patent expires, other companies may produce generics or similar drugs with the same active substance.

Each medical drug has several names – a chemical name (based on its formula), an international non-proprietary name (INN) and a brand name.

A chemical name is clear only for the specialists in a pharmaceutical industry, it means nothing for the patients. INN is the name of the active substance. It is approved by the WHO and this name must appear on the package. A brand name is the name given by the manufacturer.

A chemical name of Viagra is 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one.

INN is Sildenafil. And Viagra is a brand name given by Pfizer.

Viagra generics

Pfizer obtained the patent for Viagra in 1998 for 12 years. In 2010 the patent should have expired but it was extended several times. Currently, the patent is in force until 2020.

Nevertheless, on the US market there is an FDA approved Viagra generic. It is manufactured by TEVA since 2017. Pfizer and Teva reached agreement on the issue. The dosage is the same – 25, 50 and 100 mg.

Viagra from India

In the USA, they strictly enforce patent law unlike developing countries, especially India. Indian pharmaceutical industry is well-developed and many companies in this country manufacture Viagra analogs that are banned in the USA, Europe and other developing countries. Despite this fact, these illegal generics are still sold.

The main reason why they appear on the market is their low price. Generics are distributed through illegal online pharmacies much cheaper than original drugs.

Where can I buy Viagra? Can I buy Viagra without prescription.

Viagra is a prescription drug. It means that you should have a prescription from your doctor to buy it. If you buy Viagra in a legal online pharmacy, then you should give a scanned copy of your prescription.

Illegal online pharmacies sell Viagra generics without a prescription and for a much lower price. These pharmacies are closes from time to time by the law enforcement agencies but they appear again with a different web address.

These online pharmacies are in demand because men are not willing to go to a doctor and share their private problems. So, they buy medications in those places where a prescription is not needed.

Interesting facts about Viagra

Viagra may help babies with breathing problems

Nearly 10% of children in the USA are born prematurely or before 37 week of pregnancy. The earlier the baby is born, the higher health risks are.

The most common problem of premature babies is immature lungs. These babies need a mechanical ventilator to breathe.

Sildenafil – the active substance of Viagra – helps to widen blood vessels in the lungs making them work more efficiently.

A small dose of Viagra is enough to improve breathing and reduce ventilator settings.

Viagra improves athletic performance

The scientists have been speculating about Viagra use in sport since the day the drug was developed. Many studies were conducted with the participation of the cyclists.

The results of the studies did not show significant improvements but 2006 study was conducted at high altitudes (3.874 meters above sea level). 4 out of 10 cyclists showed 39% better performance than the other 6. One sportsman withdrew because of a severe headache.

We can come to conclusion that Viagra individually impacts the cardiovascular system during physical activities. And the differences are noticeable only at high altitudes.

Viagra protects endangered animals

We can hardly imagine a man today who would use tiger bones, rhino horns, seal penis or reindeer antler to improve his sexual life. But before bones, horns, penises, liver and other parts and organs of animals were used to treat erectile dysfunction. There was no evidence that it was helpful but ignorant people believed in the effectiveness of these remedies.

When Viagra appeared, people including the followers of Chinese medicine stopped killing animals for this purpose.

Viagra is not a sex stimulant

Viagra has no effect on a male libido. Men do not feel like having sex after taking the drug. Libido is a more complicated thing. It depends on several factors including hormonal imbalance, stress or depression, certain medications, problems with a partner, tension, sedentary lifestyle, alcohol etc.

Viagra has a positive effect on the vessels in the pelvic organs and erection occurs only when there is sexual stimulation.

Only a specialist can recommend what to do to increase libido. Probably, you may need a psychotherapy. Others require hormonal replacement therapy. In some cases, men should stop taking certain drugs affecting their libido. Men may also consider changing their lifestyle, eating healthy and regularly doing exercises.

Viagra is useless for women

There is no evidence that Viagra has a positive effect on a female sex drive. So, it is not recommended for use in women.

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